Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5575155 | 0.85 | KDM4E (0.63) | KDM4EMAOBAOC3MRGPRX4KMT2A | |
| SCHEMBL13641800 | 0.85 | KDM4E (0.63) | KDM4EL3MBTL1MAOBAOC3MRGPRX4 | |
| SCHEMBL187207 | 0.81 | KDM4E (0.59) | KDM4EL3MBTL1MAOBAOC3MRGPRX4 | |
| SCHEMBL4939704 | 0.81 | ALOX15 (0.47) | KDM4EKMT2AMEN1GAAHTT | |
| SCHEMBL8510279 | 0.81 | KDM4E (0.63) | KDM4EL3MBTL1MAOBAOC3MRGPRX4 | |
| SCHEMBL4994252 | 0.81 | ACP3 (0.51) | MAOBKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL12722064 | 0.81 | KDM4E (0.57) | KDM4EMAOBAOC3MRGPRX4KMT2A | |
| SCHEMBL11633334 | 0.80 | KDM4E (0.56) | KDM4EMAOBAOC3MRGPRX4KMT2A | |
| SCHEMBL7898440 | 0.77 | KDM4E (0.59) | KDM4EL3MBTL1MAOBAOC3MRGPRX4 | |
| SCHEMBL10015921 | 0.76 | KDM4E (0.64) | KDM4EL3MBTL1MAOBAOC3MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016136-A1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN DERIVATIVES | SIFAVITOR S.R.L. (IT) | 2012-01-19 | — | — | US | disclosed |
| EP-2401252-A1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN DERIVATIVES | Sifavitor S.r.l. (IT) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097672-A1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN DERIVATIVES | SIFAVITOR S.R.L. (IT) | 2010-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016136-A1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN DERIVATIVES | PTGIS, PTGES, PTGIR | KDM4E 4584/4885L3MBTL1 4727/4885MAOB 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.