Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.53 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.30 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.30 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.30 |
| ▸ | INPP5B | P32019 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL1994741 | 0.97 | FDPS (0.67) | FDPSBLMTDP1SLC34A1PEPD | |
| Pyrophosphoric Acid SCHEMBL9518322 | 0.93 | FDPS (0.71) | FDPSBLMTDP1SLC34A1PEPD | |
| Pyrophosphoric Acid SCHEMBL3842535 | 0.93 | FDPS (0.71) | FDPSBLMTDP1SLC34A1PEPD | |
| Pyrophosphoric Acid SCHEMBL2113857 | 0.93 | FDPS (0.71) | FDPSBLMTDP1SLC34A1PEPD | |
| Pyrophosphoric Acid SCHEMBL28159392 | 0.93 | FDPS (0.71) | FDPSBLMTDP1SLC34A1PEPD | |
| Pyrophosphoric Acid SCHEMBL15662776 | 0.93 | FDPS (0.71) | FDPSBLMTDP1SLC34A1PEPD | |
| Pyrophosphoric Acid SCHEMBL5884465 | 0.93 | FDPS (0.71) | FDPSBLMTDP1SLC34A1PEPD | |
| Pyrophosphoric Acid SCHEMBL26101622 | 0.93 | FDPS (0.71) | FDPSBLMTDP1SLC34A1PEPD | |
| Pyrophosphoric Acid SCHEMBL28511969 | 0.90 | FDPS (0.67) | FDPSBLMTDP1SLC34A1PEPD | |
| Pyrophosphoric Acid SCHEMBL28978110 | 0.90 | FDPS (0.67) | FDPSBLMTDP1SLC34A1PEPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229803-B2 | Reaction of (di)amines in the presence of a lysine oxidase and of a reducing agent | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-12 | — | — | US | disclosed |
| US-20040158061-A1 | Reaction of (di)amines in the presence of a lysine oxidase and of a reducing agent | BASF SE (DE) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158061-A1 | Reaction of (di)amines in the presence of a lysine oxidase and of a reducing agent | CBR1, CBR3, AOC2 | FDPS 4244/4885BLM 1569/4885TDP1 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.