Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576017 | 1.00 | GPR119 (0.53) | GPR119TP53HDAC1HDAC6KDM4E | |
| SCHEMBL4597324 | 0.88 | GPR119 (0.51) | GPR119TP53KDM4EMAPTTHRB | |
| SCHEMBL4724963 | 0.88 | GPR119 (0.51) | GPR119TP53KDM4EMAPTTHRB | |
| SCHEMBL4596940 | 0.85 | HDAC1 (0.47) | TP53HDAC1HDAC6KDM4EMAPT | |
| SCHEMBL4597612 | 0.83 | GPR119 (0.52) | GPR119TP53HDAC1HDAC6KDM4E | |
| SCHEMBL5576090 | 0.83 | GPR119 (0.52) | GPR119TP53HDAC1HDAC6KDM4E | |
| SCHEMBL4597778 | 0.79 | HTR2C (0.52) | TP53HDAC1HDAC6KDM4EMAPT | |
| SCHEMBL30563607 | 0.79 | GPR119 (0.65) | GPR119TP53KDM4EMAPTTHRB | |
| SCHEMBL4552609 | 0.79 | CCR5 (0.45) | GPR119 | |
| SCHEMBL29880399 | 0.74 | GPR119 (0.59) | GPR119TP53KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | GPR119 229/4885TP53 2854/4885HDAC1 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.