1-Naphthol

1-Naphthol

SCHEMBL557616

CCOCC.Oc1cccc2ccccc12

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 2/20 0.68
▸ HPGD P15428 2/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ CDC25B P30305 2/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ PTPN22 Q9Y2R2 1/20 0.42
▸ ALOX5 P09917 1/20 0.42
▸ TSHR P16473 1/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ PLAU P00749 1/20 0.41
▸ CA12 O43570 1/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CA7 P43166 1/20 0.41
▸ CA9 Q16790 1/20 0.41
▸ CA14 Q9ULX7 1/20 0.41
▸ MAPKAPK2 P49137 1/20 0.41
▸ CTDSP1 Q9GZU7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL15641910 0.93 CYP1A2 (0.59) CYP1A2HPGDALDH1A1CDC25BCYP2C9
1-Naphthol SCHEMBL16178486 0.86 CYP1A2 (0.50) CYP1A2HPGDALDH1A1CDC25BCYP2C9
1-Naphthol SCHEMBL2481329 0.85 CYP1A2 (0.77) CYP1A2HPGDALDH1A1CYP2C9CYP2C19
1-Naphthol SCHEMBL28966359 0.85 CYP1A2 (0.63) CYP1A2HPGDALDH1A1CDC25BCYP2C9
1-Naphthol SCHEMBL2017175 0.84 CYP1A2 (0.49) CYP1A2CYP2C19ALOX5KDM4ELMNA
1-Naphthol SCHEMBL28476693 0.83 CYP1A2 (0.74) CYP1A2HPGDALDH1A1CYP2C9CYP2C19
1-Naphthol SCHEMBL27983786 0.83 CYP1A2 (0.74) CYP1A2HPGDALDH1A1CYP2C9CYP2C19
1-Naphthol SCHEMBL558316 0.83 CYP1A2 (0.81) CYP1A2HPGDALDH1A1HSD17B10PTPN22
1-Naphthol SCHEMBL10627914 0.83 CYP1A2 (0.90) CYP1A2HPGDALDH1A1CYP2C9CYP2C19
1-Naphthol SCHEMBL10486461 0.82 CYP1A2 (1.00) CYP1A2HPGDALDH1A1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113788771-B Preparation method of sulfydryl modified naphthol ether dye 高密丽美生物科技有限公司 2022-04-12 — — CN claimed
CN-113788771-A Preparation method of sulfydryl modified naphthol ether dye 高密丽美生物科技有限公司 2021-12-14 — — CN claimed
US-20210221739-A1 RHEOLOGY MODIFIER KAO CORPORATION (JP) 2021-07-22 — — US claimed
CN-109970661-A A kind of synthetic method of naphthalene hydrogen bond supramolecular materials 常州大学 2019-07-05 — — CN claimed
EP-3473690-A1 RHEOLOGY MODIFIER Kao Corporation (JP) 2019-04-24 — — EP claimed
CN-109369542-A A kind of Quadrupolar hydrogen bond assembly and its synthetic method 常州大学 2019-02-22 — — CN claimed
CN-109287676-A A kind of antibacterial mite-removing removes the aqueous solution of peculiar smell 沈阳秉弘环保科技有限公司 2019-02-01 — — CN claimed
CN-109232438-A A kind of naphthol ether chain bridging urea groups pyrimidinone compound and its synthetic method 常州大学 2019-01-18 — — CN claimed
CN-109072044-A Rheology modifier 花王株式会社 2018-12-21 — — CN claimed
CN-108485812-A A kind of daily use chemicals lemon orange essence and its preparation method 广东铭康香精香料有限公司 2018-09-04 — — CN claimed
US-20080108732-A1 Polycondensation Product Base on Aromatic or Heteroaromatic Compounds, Method for the Production Thereof, and Use Thereof CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2008-05-08 — — US claimed
CN-101061151-A Polycondensation products based on aromatic or heteroaromatic compounds, method for the production and use thereof CONSTR RES & TECH GMBH (DE) 2007-10-24 — — CN claimed
CN-1315781-C Preparation of 4-amino-1-naphthol ethers BAYER CHEMICALS AG (DE) 2007-05-16 — — CN claimed
US-20050261498-A1 Preparation of 4-amino-1-naphthol ethers KOMOSCHINSKI JOACHIM 2005-11-24 — — US claimed
CN-1572335-A Self-Service respiratory vaccination instrument for SARS infectious disease CONG FANZI (CN) 2005-02-02 — — CN claimed
CN-1547568-A Method for preparing 4-amino-1-naphthol ether compound ˹���ػ�ѧ��Ʒ�ɷ����޹�˾ 2004-11-17 — — CN claimed
CN-1520846-A Quick-effective aerosol with plant aroma and its preparation 丛繁滋 2004-08-18 — — CN claimed
CN-1500477-A Quick result aerosol with plant aroma and its preparation 丛繁滋 2004-06-02 — — CN claimed
CN-1475204-A Medicinal Composition, dry powder vapor, nebula, nebula auxiliary preparation for use through mouth and nose and its preparation method 丛繁滋 2004-02-18 — — CN claimed
US-20030083525-A1 Preparation of 4-amino-1-naphthol ethers LANXESS DEUTSCHLAND GMBH (DE) 2003-05-01 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050261498-A1 Preparation of 4-amino-1-naphthol ethers NAP1L4, NAAA, NPEPPS CYP1A2 65/4885HPGD 2004/4885ALDH1A1 516/4885
US-20030083525-A1 Preparation of 4-amino-1-naphthol ethers NAP1L4, NAAA, NPEPPS CYP1A2 65/4885HPGD 2004/4885ALDH1A1 516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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