Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12854020 | 0.77 | MAOB (0.71) | MAOBMAOAPTPRCPTPN1ADRA2A | |
| SCHEMBL61411 | 0.77 | MAOB (0.71) | MAOBMAOAPTPRCPTPN1ADRA2A | |
| SCHEMBL17843529 | 0.76 | NPC1 (0.56) | MAOBMAOAPTPRCPTPN1ADRA2A | |
| SCHEMBL7089566 | 0.74 | MAOB (0.54) | MAOBMAOAPTPRCPTPN1ADRA2A | |
| SCHEMBL30417366 | 0.74 | RAB9A (0.68) | MAOBMAOAPTPRCPTPN1KMT2A | |
| SCHEMBL6590629 | 0.72 | MAOB (0.56) | MAOBMAOAPTPRCPTPN1BRD4 | |
| SCHEMBL8764553 | 0.72 | HPGD (0.54) | MAOBMAOAPTPRCPTPN1KMT2A | |
| SCHEMBL30036439 | 0.72 | MAOB (0.63) | MAOBMAOAPTPRCPTPN1ADRA2A | |
| SCHEMBL103158 | 0.72 | MAOB (0.63) | MAOBMAOAPTPRCPTPN1ADRA2A | |
| SCHEMBL3048109 | 0.72 | MAOB (0.51) | MAOBMAOAPTPRCPTPN1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060606-A1 | Compounds and methods for modulating phosphodiesterase 10A | DALHOUSIE UNIVERSITY (CA) | 2007-03-15 | — | — | US | disclosed |
| JP-2000128878-A | BENZOFURYL-ALPHA-PYRIDONE DERIVATIVE | TEIJIN LTD | 2000-05-09 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060606-A1 | Compounds and methods for modulating phosphodiesterase 10A | PDE7A, PDE10A, PDE2A | MAOB 111/4885MAOA 145/4885PTPRC 1425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.