Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099810 | 0.85 | MAPT (0.52) | PBRM1LMNAPOLBCA1CA2 | |
| SCHEMBL11788105 | 0.84 | PBRM1 (0.68) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL5577009 | 0.77 | MAPT (0.50) | NPC1POLBCA1CA2CA9 | |
| SCHEMBL9282073 | 0.76 | PBRM1 (0.87) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL29363032 | 0.76 | PBRM1 (0.87) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL125621 | 0.76 | PBRM1 (0.87) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL9101086 | 0.74 | PBRM1 (0.83) | PBRM1NPC1MITFLMNAPOLB | |
| Hydrochloric Acid SCHEMBL8643223 | 0.74 | PBRM1 (0.83) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL29492479 | 0.74 | PBRM1 (0.83) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL204263 | 0.74 | PBRM1 (0.83) | PBRM1NPC1MITFLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070003987-A1 | Screening method for substance binding to merozoite surface protein-1/42 | MEDICAL RESEARCH COUNCIL (GB) | 2007-01-04 | — | — | US | claimed |
| US-20070003987-A1 | Screening method for substance binding to merozoite surface protein-1/42 | MEDICAL RESEARCH COUNCIL (GB) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070003987-A1 | Screening method for substance binding to merozoite surface protein-1/42 | CD2BP2, MASP2, CD14 | PBRM1 1838/4885NPC1 1935/4885MITF 2189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.