Urea

Urea

SCHEMBL5577087

NC(N)=O.NC(N)=S.OB(O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
ATM Q13315 1/20 0.50
ATR Q13535 1/20 0.50
ALDH1A1 P00352 1/20 0.50
OR51E2 Q9H255 1/20 0.50
ACHE P22303 1/20 0.36
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
TAS2R38 P59533 1/20 0.33
LDHA P00338 1/20 0.31
LDHB P07195 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL20359695 0.87 LMNA (0.67) LMNATSHRTDP1ALDH1A1OR51E2
Urea SCHEMBL780636 0.87
Urea SCHEMBL653170 0.87
Urea SCHEMBL28602962 0.87 ALDH1A1 (0.67) LMNATSHRTDP1ATMATR
Urea SCHEMBL1308629 0.82
Urea SCHEMBL28892097 0.78 ALDH1A1 (0.55) LMNATSHRTDP1ATMATR
Urea SCHEMBL28340041 0.78 ALDH1A1 (0.55) LMNATSHRTDP1ATMATR
Urea SCHEMBL1131239 0.78 ALDH1A1 (0.55) LMNATSHRTDP1ATMATR
Urea SCHEMBL6264282 0.78 ALDH1A1 (0.55) LMNATSHRTDP1ATMATR
Urea SCHEMBL28106114 0.78 ALDH1A1 (0.55) LMNATSHRTDP1ATMATR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8697604-B2 Labeling agents for mass spectrometry comprising tertiary amines ELECTROPHORETICS LIMITED (GB) 2014-04-15 US disclosed
EP-1606623-B1 LABELLING AGENTS FOR MASS SPECTROMETRY COMPRISING TERTIARY AMINES ELECTROPHORETICS LTD (GB) 2013-05-22 EP disclosed
US-20070023628-A1 Labeling agents for mass spectrometry comprising tertiary amines ELECTROPHORETICS LIMITED (GB) 2007-02-01 US disclosed
EP-1606623-A2 LABELLING AGENTS FOR MASS SPECTROMETRY COMPRISING TERTIARY AMINES Xzillion GmbH & CO.KG (DE) 2005-12-21 EP disclosed
WO-2004086050-A2 LABELLING AGENTS FOR MASS SPECTROMETRY COMPRISING TERTIARY AMINES XZILLION GMBH & CO. KG (DE) 2004-10-07 WO disclosed