SCHEMBL8612645

SCHEMBL8612645

Cc1ccc(CN[C@@H](CCC(=O)O)C(=O)O)cc1

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.50
MEP1B Q16820 2/20 0.48
NAALAD2 Q9Y3Q0 3/20 0.47
FOLH1 Q04609 9/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
RIMKLA Q8IXN7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2250167 0.88 L3MBTL1 (0.51) FFAR1SMN1; SMN2
SCHEMBL2250165 0.88 FFAR1 (0.48) FFAR1MEP1BSMN1; SMN2
SCHEMBL1818651 0.85 NAALAD2 (0.60) MEP1BNAALAD2FOLH1RIMKLA
SCHEMBL3387298 0.85 NAALAD2 (0.60) MEP1BNAALAD2FOLH1RIMKLA
SCHEMBL869873 0.85 NAALAD2 (0.60) MEP1BNAALAD2FOLH1RIMKLA
SCHEMBL6566486 0.84 FOLH1 (0.61) FFAR1MEP1BNAALAD2FOLH1
SCHEMBL5577137 0.84 MEP1B (0.48) MEP1BNAALAD2FOLH1RIMKLA
SCHEMBL5577139 0.84 MEP1B (0.48) MEP1BNAALAD2FOLH1RIMKLA
SCHEMBL6051729 0.84 SMN1; SMN2 (0.45) FFAR1SMN1; SMN2
SCHEMBL31229321 0.84 FFAR1 (0.53) FFAR1MEP1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5776901-A Polypeptide analogues having growth hormone releasing activity ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 1998-07-07 US disclosed
US-5663146-A ADMINISTERING A SYNERGISTIC COMBINATION TO ANIMALS, INCLUDING HUMANS ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 1997-09-02 US disclosed
US-5534494-A Polypeptide compounds having growth hormone releasing activity POLYGEN HOLDING CORPORATION (US) 1996-07-09 US disclosed
US-5486505-A Polypeptide compounds having growth hormone releasing activity POLYGEN HOLDING CORPORATION (US) 1996-01-23 US disclosed
US-4880777-A ANIMAL GROWTH, SOMATOTROPIN EASTMAN KODAK COMPANY (US) 1989-11-14 US disclosed
US-4839344-A Polypeptide compounds having growth hormone releasing activity EASTMAN KODAK COMPANY (US) 1989-06-13 US disclosed