Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1789696 | 0.82 | RPS6KB1 (0.43) | RPS6KB1AKT1 | |
| SCHEMBL1794254 | 0.74 | RPS6KB1 (0.43) | RPS6KB1AKT1 | |
| SCHEMBL4925823 | 0.69 | GPR119 (0.40) | — | |
| SCHEMBL4930413 | 0.67 | ALDH1A1 (0.35) | — | |
| SCHEMBL1792345 | 0.67 | RPS6KB1 (0.62) | RPS6KB1AKT1 | |
| SCHEMBL5577196 | 0.65 | RPS6KB1 (0.44) | RPS6KB1AKT1 | |
| Ether SCHEMBL4929772 | 0.64 | AMD1 (0.31) | — | |
| SCHEMBL1792249 | 0.61 | RPS6KB1 (0.56) | RPS6KB1AKT1 | |
| SCHEMBL1792988 | 0.61 | RPS6KB1 (0.46) | RPS6KB1AKT1 | |
| SCHEMBL1791694 | 0.61 | RPS6KB1 (0.65) | RPS6KB1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1750727-A2 | KINASE MODULATORS AND METHODS OF USE | Exelixis, Inc. (US) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005117909-A2 | KINASE MODULATORS AND METHODS OF USE | EXELIXIS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |