Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577482 | 0.91 | SIGMAR1 (0.43) | SIGMAR1CACNA1GGAAACHEKDM4E | |
| SCHEMBL5577920 | 0.90 | MEN1 (0.48) | SIGMAR1CACNA1GCHRM4 | |
| SCHEMBL5577281 | 0.88 | ACHE (0.48) | SIGMAR1CACNA1GMCHR1GAAACHE | |
| SCHEMBL5577663 | 0.88 | ACHE (0.49) | SIGMAR1ALDH1A1L3MBTL1GAAACHE | |
| SCHEMBL5577819 | 0.88 | ACHE (0.46) | SIGMAR1ALDH1A1MCHR1ACHEKDM4E | |
| SCHEMBL5577273 | 0.88 | SIGMAR1 (0.45) | SIGMAR1ALDH1A1L3MBTL1MCHR1GAA | |
| SCHEMBL5577520 | 0.88 | SIGMAR1 (0.45) | SIGMAR1CACNA1GMCHR1GAAKDM4E | |
| SCHEMBL5577913 | 0.86 | HRH3 (0.50) | SIGMAR1ACHE | |
| SCHEMBL5577478 | 0.85 | ACHE (0.43) | SIGMAR1MCHR1ACHE | |
| SCHEMBL5577870 | 0.84 | SIGMAR1 (0.47) | SIGMAR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | SIGMAR1 3281/4885CACNA1G 4769/4885ALDH1A1 1147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.