Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577281 | 0.94 | ACHE (0.48) | ACHEMCHR1SIGMAR1HRH3KDM4E | |
| SCHEMBL5577913 | 0.93 | HRH3 (0.50) | ACHESIGMAR1HRH3MEN1KMT2A | |
| SCHEMBL5577478 | 0.91 | ACHE (0.43) | ACHEMCHR1SIGMAR1HRH3KMT2A | |
| SCHEMBL5577274 | 0.91 | CACNA1G (0.47) | ACHEOPRM1SIGMAR1MEN1MAPK1 | |
| SCHEMBL5577702 | 0.89 | MCHR1 (0.51) | MCHR1SIGMAR1HRH3ALDH1A1KDM4E | |
| SCHEMBL5577790 | 0.88 | ACHE (0.56) | ACHEMCHR1OPRM1SIGMAR1ALDH1A1 | |
| SCHEMBL5577338 | 0.88 | SIGMAR1 (0.43) | ACHEMCHR1SIGMAR1ALDH1A1KDM4E | |
| SCHEMBL5577751 | 0.88 | ACHE (0.47) | ACHEMCHR1OPRM1SIGMAR1HRH3 | |
| SCHEMBL5577870 | 0.87 | SIGMAR1 (0.47) | ACHESIGMAR1HRH3KCNH2 | |
| SCHEMBL5577482 | 0.86 | SIGMAR1 (0.43) | ACHESIGMAR1HRH3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | ACHE 1504/4885MCHR1 4381/4885OPRM1 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.