Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577631 | 0.91 | ACHE (0.52) | ACHESIGMAR1CCR5MEN1KMT2A | |
| SCHEMBL5577665 | 0.91 | ACHE (0.59) | ACHESIGMAR1MEN1KMT2AGAA | |
| SCHEMBL5577500 | 0.90 | SIGMAR1 (0.48) | ACHESIGMAR1CCR5MEN1KMT2A | |
| SCHEMBL5577523 | 0.90 | ACHE (0.56) | ACHESIGMAR1MEN1KMT2AGAA | |
| SCHEMBL5577870 | 0.89 | SIGMAR1 (0.47) | ACHESIGMAR1CCR5 | |
| SCHEMBL5577412 | 0.89 | ACHE (0.60) | ACHESIGMAR1MEN1KMT2AATM | |
| SCHEMBL5577790 | 0.86 | ACHE (0.56) | ACHESIGMAR1MEN1KMT2AGAA | |
| SCHEMBL5577885 | 0.85 | SIGMAR1 (0.52) | ACHESIGMAR1CCR5GAA | |
| SCHEMBL5577437 | 0.84 | ACHE (0.49) | ACHESIGMAR1MEN1KMT2AATM | |
| SCHEMBL5577775 | 0.84 | ALDH1A1 (0.47) | ACHESIGMAR1CCR5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | ACHE 1504/4885SIGMAR1 3281/4885CCR5 183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.