Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | KLK1 | P06870 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 7/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577616 | 0.96 | KLKB1 (0.52) | OPRM1OPRK1KLKB1KLK1CXCR3 | |
| SCHEMBL5577757 | 0.86 | MCHR1 (0.49) | MCHR1DRD2DRD4DRD3 | |
| SCHEMBL5577580 | 0.84 | MAPT (0.62) | MCHR1HTR2AHTR1ADRD2DRD4 | |
| SCHEMBL5577719 | 0.83 | CHRM3 (0.55) | MCHR1CXCR3HTR2AHTR1ADRD2 | |
| SCHEMBL5577406 | 0.83 | MT-CO2 (0.47) | OPRM1OPRK1KLKB1KLK1CHRM3 | |
| SCHEMBL5577317 | 0.82 | GAA (0.51) | MCHR1DRD2DRD4DRD3CHRM3 | |
| SCHEMBL5577690 | 0.81 | CXCR3 (0.58) | KLKB1KLK1CXCR3KCNH2HRH3 | |
| SCHEMBL5577898 | 0.81 | CXCR3 (0.48) | KLKB1KLK1CXCR3DRD2DRD4 | |
| SCHEMBL5577844 | 0.81 | SCN10A (0.56) | OPRM1OPRK1MCHR1CXCR3HTR2A | |
| SCHEMBL5577738 | 0.80 | OPRM1 (0.52) | OPRM1OPRK1MCHR1CXCR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | OPRM1 584/4885OPRK1 353/4885KLKB1 2759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.