Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577611 | 0.86 | MEN1 (0.59) | ALDH1A1MEN1KMT2ADRD2ACKR3 | |
| SCHEMBL5577618 | 0.85 | CHRM3 (0.60) | HPGDMEN1KMT2ADRD2ACKR3 | |
| SCHEMBL5577607 | 0.84 | ACHE (0.57) | ALDH1A1HPGDMEN1KMT2ATP53 | |
| SCHEMBL5577612 | 0.83 | CHRM3 (0.56) | MEN1KMT2ADRD2ACKR3CHRM3 | |
| SCHEMBL5577353 | 0.83 | CHRM3 (0.56) | MEN1KMT2ADRD2ACKR3CHRM3 | |
| SCHEMBL5577378 | 0.82 | DRD4 (0.64) | MEN1KMT2AACKR3CHRM3MCHR1 | |
| SCHEMBL5577693 | 0.81 | CHRM3 (0.54) | MEN1KMT2ADRD2ACKR3CHRM3 | |
| SCHEMBL5577563 | 0.80 | DRD2 (0.58) | MEN1KMT2ATP53DRD2ACKR3 | |
| SCHEMBL5577405 | 0.80 | CCR2 (0.65) | MEN1KMT2ACHRM3CHRM4 | |
| SCHEMBL5577381 | 0.78 | CHRM3 (0.53) | ALDH1A1MEN1KMT2ADRD2ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | ALDH1A1 1147/4885HPGD 855/4885MEN1 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.