Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577591 | 0.96 | DRD4 (0.42) | HTR4NPC1RAB9ASIGMAR1ACKR3 | |
| SCHEMBL5577431 | 0.88 | MT-CO2 (0.46) | HTR4SIGMAR1ACKR3CACNA1GALDH1A1 | |
| SCHEMBL5577778 | 0.86 | ALDH1A1 (0.44) | KDM4EALDH1A1LMNASMN1; SMN2ABCB1 | |
| SCHEMBL5577850 | 0.85 | LMNA (0.45) | HTR4NPC1RAB9ASIGMAR1ACKR3 | |
| SCHEMBL5577683 | 0.85 | LMNA (0.49) | SIGMAR1ACKR3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5577502 | 0.85 | KDM4E (0.41) | HTR4JAK1JAK3CACNA1GKDM4E | |
| SCHEMBL5577587 | 0.84 | MT-CO2 (0.45) | HTR4RAB9ASIGMAR1ACKR3LMNA | |
| SCHEMBL5577827 | 0.84 | ALDH1A1 (0.42) | KDM4EALDH1A1LMNASMN1; SMN2ABCB1 | |
| SCHEMBL5577633 | 0.83 | JAK1 (0.43) | HTR4NPC1RAB9ASIGMAR1ACKR3 | |
| SCHEMBL5577735 | 0.83 | LMNA (0.46) | NPC1RAB9ASIGMAR1ACKR3JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | HTR4 2137/4885NPC1 799/4885RAB9A 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.