Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577824 | 0.93 | SIGMAR1 (0.48) | SIGMAR1CHRM3SLC6A12TMEM97MCHR1 | |
| SCHEMBL5577528 | 0.93 | SIGMAR1 (0.48) | SIGMAR1CHRM3SLC6A12TMEM97MCHR1 | |
| SCHEMBL5577846 | 0.92 | MT-CO2 (0.51) | SIGMAR1SLC6A12TMEM97MCHR1HTR4 | |
| SCHEMBL5577759 | 0.91 | SIGMAR1 (0.48) | SIGMAR1SLC6A12TMEM97MCHR1HTR4 | |
| SCHEMBL5577726 | 0.90 | SIGMAR1 (0.51) | SIGMAR1SLC6A12TMEM97MCHR1PRKAA2 | |
| SCHEMBL5577515 | 0.89 | POLB (0.53) | SIGMAR1SLC6A12TMEM97MCHR1MEN1 | |
| SCHEMBL5577565 | 0.87 | CCR3 (0.55) | SIGMAR1SLC6A12TMEM97MCHR1KMT2A | |
| SCHEMBL5577504 | 0.87 | SIGMAR1 (0.51) | SIGMAR1SLC6A12TMEM97MCHR1KMT2A | |
| SCHEMBL5577399 | 0.87 | SIGMAR1 (0.53) | SIGMAR1SLC6A12TMEM97MCHR1ERCC1 | |
| SCHEMBL5577350 | 0.87 | LMNA (0.51) | SIGMAR1CHRM3SLC6A12TMEM97MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | SIGMAR1 3281/4885CHRM3 2099/4885SLC6A12 2295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.