Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577381 | 0.89 | CHRM3 (0.53) | DRD2MEN1KMT2ACCR2 | |
| SCHEMBL5577360 | 0.85 | MCHR1 (0.60) | MEN1KMT2AKCNH2 | |
| SCHEMBL5577695 | 0.84 | CCR2 (0.52) | DRD2MEN1KMT2ACCR2 | |
| SCHEMBL5577353 | 0.84 | CHRM3 (0.56) | DRD2MEN1KMT2ACCR2 | |
| SCHEMBL5577457 | 0.83 | KCNH2 (0.51) | MEN1KMT2ACCR2KCNH2HRH3 | |
| SCHEMBL5577315 | 0.83 | GAA (0.57) | POLBKCNH2 | |
| SCHEMBL5577864 | 0.82 | ALDH1A1 (0.52) | MEN1KMT2AKCNH2HRH3 | |
| SCHEMBL5577369 | 0.82 | MAPT (0.57) | MEN1KMT2ACCR2KCNH2HRH3 | |
| SCHEMBL5577358 | 0.81 | DRD2 (0.46) | DRD2MEN1KMT2ACCR2KCNH2 | |
| SCHEMBL5577923 | 0.81 | HTR2C (0.46) | DRD2MEN1KMT2ACCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | DRD2 4468/4885MEN1 748/4885KMT2A 3527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.