Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577488 | 0.94 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DCHRM3 | |
| SCHEMBL5577848 | 0.88 | LMNA (0.45) | PDE4APDE4BPDE4CPDE4DCHRM3 | |
| SCHEMBL5577294 | 0.88 | MT-CO2 (0.49) | CHRM3OPRL1LMNAKMT2AMEN1 | |
| SCHEMBL5577536 | 0.87 | DRD2 (0.42) | PDE4APDE4BPDE4CPDE4DCHRM3 | |
| SCHEMBL5577460 | 0.87 | CHRM3 (0.50) | PDE4APDE4BPDE4CPDE4DCHRM3 | |
| SCHEMBL5577453 | 0.85 | LMNA (0.45) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL5577863 | 0.84 | KDM4E (0.39) | PDE4APDE4BPDE4CPDE4DCHRM3 | |
| SCHEMBL5577521 | 0.84 | KDM4E (0.41) | PDE4APDE4BPDE4CPDE4DCHRM3 | |
| SCHEMBL5577480 | 0.81 | MT-CO2 (0.54) | CHRM3OPRL1KMT2AMEN1KDM4E | |
| SCHEMBL5577799 | 0.80 | LMNA (0.45) | CHRM3LMNAHPGDAPEX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1616862-A1 | NITROGENOUS HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043079-A1 | Heterocyclic compound containing nitrogen atom and use thereof | HLA-DRB1, MIF, HLA-C | PDE4A 2783/4885PDE4B 3397/4885PDE4C 3607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.