Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.61 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5578139 | 0.99 | MCHR1 (0.60) | MCHR1ACHEHTR1ADRD2HTR2A | |
| Trifluoroacetic Acid SCHEMBL6807242 | 0.94 | MCHR1 (0.57) | MCHR1ACHEHTR1ADRD2HTR2A | |
| SCHEMBL6909910 | 0.89 | ACHE (0.54) | MCHR1ACHEHTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL8791840 | 0.83 | ACHE (0.70) | MCHR1ACHEHTR1ADRD2HTR2A | |
| Trifluoroacetic Acid SCHEMBL6807470 | 0.81 | MCHR1 (0.57) | MCHR1ACHEHTR1ADRD2HTR2A | |
| Trifluoroacetic Acid SCHEMBL6807234 | 0.80 | MCHR1 (0.54) | MCHR1ACHEHTR1ADRD2HTR2A | |
| SCHEMBL5578409 | 0.80 | MCHR1 (0.71) | MCHR1ACHEHTR1ADRD2HTR2A | |
| SCHEMBL5578112 | 0.79 | MCHR1 (0.73) | MCHR1ACHEHTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL5578294 | 0.79 | MCHR1 (0.70) | MCHR1ACHEHTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL5578270 | 0.78 | MCHR1 (0.72) | MCHR1ACHEHTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232538-A1 | Uses of polypeptides | TAKEDA PHARMACEUTICAL COMPANY, LTD (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20040063699-A1 | Gpr14 antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-01 | — | — | US | disclosed |
| US-20040053826-A1 | Uses of polypeptides | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1310490-A1 | GPR14 ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2003-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232538-A1 | Uses of polypeptides | NPSR1, SCTR, GRPR | MCHR1 38/4885ACHE 2825/4885HTR1A 83/4885 |
| US-20040053826-A1 | Uses of polypeptides | NPSR1, SCTR, GRPR | MCHR1 38/4885ACHE 2825/4885HTR1A 83/4885 |
| US-20040063699-A1 | Gpr14 antagonist | GPR142, GPR139, GPR4 | MCHR1 191/4885ACHE 4719/4885HTR1A 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.