Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL386101 | 0.82 | GPR119 (0.51) | ALDH1A1GPR119THRBFFAR4OPRK1 | |
| SCHEMBL389030 | 0.79 | GPR119 (0.50) | ALDH1A1GPR119THRBFFAR4POLB | |
| SCHEMBL389349 | 0.71 | GPR119 (0.52) | ALDH1A1GPR119POLBL3MBTL1MAPT | |
| SCHEMBL387972 | 0.70 | GPR119 (0.68) | ALDH1A1GPR119L3MBTL1MAPTHPGD | |
| SCHEMBL14017958 | 0.70 | MAPT (0.48) | ALDH1A1GPR119TDP1MAPTHPGD | |
| SCHEMBL389055 | 0.70 | GPR119 (0.58) | ALDH1A1GPR119MAPT | |
| SCHEMBL4703671 | 0.70 | GPR119 (0.40) | ALDH1A1GPR119FFAR4L3MBTL1MAPT | |
| SCHEMBL389089 | 0.70 | MAPT (0.61) | ALDH1A1GPR119MAPT | |
| SCHEMBL389248 | 0.69 | GPR119 (0.56) | ALDH1A1GPR119THRBPOLBL3MBTL1 | |
| SCHEMBL4704968 | 0.69 | GPR119 (0.54) | ALDH1A1GPR119OPRK1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066590-A1 | Phenyl-and pyridylpiperidine-derivatives as modulators of glucose metabolism | ARENA PHARMACEUTICALS, INC. | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066590-A1 | Phenyl-and pyridylpiperidine-derivatives as modulators of glucose metabolism | GPR119, PC, PLPBP | ALDH1A1 260/4885GPR119 1/4885THRB 820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.