Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144925 | 0.81 | LMNA (0.39) | NR3C1CYP3A4KEAP1NFE2L2LMNA | |
| SCHEMBL1144923 | 0.80 | LMNA (0.39) | NR3C1CYP3A4KEAP1NFE2L2LMNA | |
| SCHEMBL10389013 | 0.77 | CYP3A4 (0.36) | NR3C1CYP3A4TSHRRECQLKEAP1 | |
| SCHEMBL27633996 | 0.77 | ATP4A (0.35) | NR3C1CYP3A4TSHRMAPTHTT | |
| Sulfuric Acid SCHEMBL9311042 | 0.74 | TRPV1 (0.41) | NR3C1CYP3A4TSHRRECQLKEAP1 | |
| SCHEMBL10799202 | 0.71 | LMNA (0.40) | NR3C1CYP3A4TSHRKEAP1NFE2L2 | |
| SCHEMBL4585693 | 0.71 | POLB (0.37) | RECQLKEAP1NFE2L2LMNAMEN1 | |
| SCHEMBL8283700 | 0.71 | CYP3A4 (0.43) | CYP3A4TSHRRECQLELANEMEN1 | |
| SCHEMBL19122441 | 0.70 | MAPT (0.43) | CYP3A4TSHRRECQLELANEMEN1 | |
| SCHEMBL8090652 | 0.70 | CYP3A4 (0.40) | CYP3A4TSHRRECQLKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1930286-A | Process for biochemical production of glyoxylic acid | KANEGAFUCHI CHEMICAL IND (JP) | 2007-03-14 | — | — | CN | disclosed |
| US-20070026510-A1 | Process for biochemical production of glyoxylic acid | KANEKA CORPORATION (JP) | 2007-02-01 | — | — | US | disclosed |
| EP-1593739-A1 | PROCESS FOR BIOCHEMICAL PRODUCTION OF GLYOXYLIC ACID | KANEKA CORPORATION (JP) | 2005-11-09 | — | — | EP | disclosed |
| US-20050170481-A1 | Novel (d)-2-hydroxy-acid oxidase derived from microorganism and biochemical process for producing glyoxylic acid therewith | KANEKA CORPORATION (JP) | 2005-08-04 | — | — | US | disclosed |
| EP-1507001-A1 | NOVEL (D)-2-HYDROXY ACID OXIDASE DERIVED FROM MICROORGANISM AND BIOCHEMICAL PROCESS FOR PRODUCING GLYOXYLIC ACID THEREWITH | Kaneka Corporation (JP) | 2005-02-16 | — | — | EP | disclosed |
| EP-0257986-B1 | PYRUVATE OXIDASE HAVING HIGH THERMAL STABILITY, ANALYTICAL METHODS USING IT AND ANALYTICAL REAGENTS CONTAINING IT | Toyo Boseki Kabushiki Kaisha (JP) | 1993-10-13 | — | — | EP | disclosed |
| US-4965194-A | Pyruvate oxidase and an analytical method using the same | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0257986-A2 | Pyruvate oxidase having high thermal stability, analytical methods using it and analytical reagents containing it | Toyo Boseki Kabushiki Kaisha (JP) | 1988-03-02 | — | — | EP | disclosed |