Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL393937 | 0.93 | — | — | |
| Guanidine SCHEMBL28942 | 0.93 | — | — | |
| Guanidine SCHEMBL28279993 | 0.93 | CA1 (0.50) | CA1CA2 | |
| Guanidine SCHEMBL2929472 | 0.93 | CA1 (0.50) | CA1CA2 | |
| Guanidine SCHEMBL27608132 | 0.93 | CA1 (0.50) | CA1CA2 | |
| Guanidine SCHEMBL23069845 | 0.93 | CA1 (0.50) | CA1CA2 | |
| Guanidine SCHEMBL6364290 | 0.89 | — | — | |
| Guanidine SCHEMBL6471890 | 0.89 | — | — | |
| Guanidine SCHEMBL21001927 | 0.89 | — | — | |
| Guanidine SCHEMBL3669881 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8980272-B2 | Antibody targeting osteoclast-associated protein | SANKYO COMPANY, LIMITED (JP) | 2015-03-17 | — | — | US | disclosed |
| EP-1715038-B1 | Antibody targeting osteoclast-associated protein | SANKYO CO (JP) | 2013-04-24 | — | — | EP | disclosed |
| US-20070081974-A1 | Antibody targeting osteoclast-associated protein | SANKYO COMPANY, LIMITED (JP) | 2007-04-12 | — | — | US | disclosed |
| EP-1715038-A1 | ANTIBODY TARGETING OSTEOCLAST-ASSOCIATED PROTEIN | Sankyo Company, Limited (JP) | 2006-10-25 | — | — | EP | disclosed |