Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 5/20 | 0.31 |
| ▸ | CTSD | P07339 | 2/20 | 0.31 |
| ▸ | CTSE | P14091 | 2/20 | 0.31 |
| ▸ | PGC | P20142 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192026 | 0.88 | MEN1 (0.32) | SMN1; SMN2ALDH1A1KMT2AKDM1AMAPT | |
| SCHEMBL6711335 | 0.87 | PKM (0.30) | — | |
| SCHEMBL9163093 | 0.86 | MAPT (0.35) | CYP1A2MAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1255774 | 0.84 | CYP2C19 (0.35) | SMN1; SMN2LMNATSHRALDH1A1KMT2A | |
| SCHEMBL2790033 | 0.82 | CYP2C19 (0.36) | SMN1; SMN2KDM4ELMNATSHRALDH1A1 | |
| SCHEMBL6257255 | 0.81 | — | — | |
| SCHEMBL2802019 | 0.80 | KDM1A (0.31) | KDM4ECYP1A2KDM1ASLC6A2SLC6A4 | |
| SCHEMBL8209205 | 0.79 | — | — | |
| SCHEMBL2678828 | 0.79 | CYP1A2 (0.33) | SMN1; SMN2CYP1A2TSHRNPC1MAPT | |
| SCHEMBL9190411 | 0.78 | TSPO (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312008-B2 | High-performance surface layer for photoreceptors | XEROX CORPORATION (US) | 2007-12-25 | — | — | US | disclosed |
| US-20060177748-A1 | High-performance surface layer for photoreceptors | XEROX CORPORATION (US) | 2006-08-10 | — | — | US | disclosed |