SCHEMBL1255774

SCHEMBL1255774

Cc1ccc(N(c2ccccc2)C2(N(c3ccccc3)c3ccc(C)cc3)C=CC(c3ccccc3)C=C2)cc1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.35
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
TSHR P16473 2/20 0.31
ALDH1A1 P00352 2/20 0.31
LMNA P02545 1/20 0.31
ALOX12 P18054 1/20 0.31
ACHE P22303 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HDAC4 P56524 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2790033 0.98 CYP2C19 (0.36) CYP2C19CA12CA9TSHRALDH1A1
SCHEMBL9190411 0.88 TSPO (0.31)
SCHEMBL6711335 0.87 PKM (0.30)
SCHEMBL710236 0.86 ALDH1A1 (0.33) CYP2C19ALDH1A1ACHEHDAC4MEN1
SCHEMBL1144651 0.84 RAB9A (0.30) CYP2C19ALDH1A1
SCHEMBL15514366 0.84 RAB9A (0.30) CYP2C19ALDH1A1
SCHEMBL5579448 0.84 HTT (0.33) TSHRALDH1A1LMNASMN1; SMN2KMT2A
SCHEMBL7624192 0.84 CYP2C19 (0.35) CYP2C19TSHRALDH1A1LMNAALOX12
SCHEMBL8325762 0.83 DRD2 (0.33) LMNA
SCHEMBL7623046 0.81 CYP2C19 (0.33) CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10177324-B2 White organic electroluminescent device and preparation method thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2019-01-08 US disclosed
US-20180248138-A1 WHITE ORGANIC ELECTROLUMINESCENT DEVICE AND PREPARATION METHOD THEREOF CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2018-08-30 US disclosed
US-7879517-B2 Photosensitive layer on support; mixture of charge transport comopund comprising N,N'-bis-(4-methylphenyl)-N,N'-biphenyl-1,1'-biphenyl-4,4'-diamine or derivative and charge generating compound comprising Y-titanyl phthalocyanine; coating semiconductor zirconium dioxide particles of specific size KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-02-01 US disclosed
US-20080057427-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-03-06 US disclosed