SCHEMBL9192026

SCHEMBL9192026

Clc1cc(Cl)cc(N(c2ccccc2)C2(N(c3ccccc3)c3cc(Cl)cc(Cl)c3)C=CC(c3ccccc3)C=C2)c1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ATM Q13315 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9163093 0.90 MAPT (0.35) MAPT
SCHEMBL5579448 0.88 HTT (0.33) ALDH1A1MAPTALOX15KMT2AHSD17B10
SCHEMBL2678828 0.82 CYP1A2 (0.33) MAPTSMN1; SMN2
SCHEMBL9190411 0.82 TSPO (0.31)
SCHEMBL6711335 0.81 PKM (0.30)
SCHEMBL6257255 0.79
SCHEMBL8211332 0.78 CYP1A2 (0.32) MEN1ALDH1A1KMT2AHSD17B10
SCHEMBL9190810 0.78 TSHR (0.34) MEN1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL1255774 0.78 CYP2C19 (0.35) MEN1ALDH1A1ALOX12KMT2ASMN1; SMN2
SCHEMBL2802019 0.78 KDM1A (0.31) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0390196-B1 Electrophotosensitive material MITA INDUSTRIAL CO LTD (JP) 1995-09-20 EP disclosed
EP-0385440-B1 Electrophotosensitive material MITA INDUSTRIAL CO LTD (JP) 1995-05-03 EP disclosed
US-5153088-A High sensitivity mixture also with charge transferring substituted phenyl diamines MITA INDUSTRIAL CO., LTD. (JP) 1992-10-06 US disclosed
US-5059503-A Used for copying machine MITA INDUSTRIAL CO., LTD. (JP) 1991-10-22 US disclosed
EP-0390196-A2 Electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1990-10-03 EP disclosed
EP-0385440-A2 Electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1990-09-05 EP disclosed