Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMAD3 | P84022 | 1/20 | 0.39 |
| ▸ | GNG2 | P59768 | 1/20 | 0.35 |
| ▸ | GNB1 | P62873 | 1/20 | 0.35 |
| ▸ | STK17B | O94768 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GLB1 | P16278 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682554 | 0.87 | SMAD3 (0.40) | SMAD3GNG2GNB1CYP3A4THRB | |
| SCHEMBL29131280 | 0.78 | SMAD3 (0.43) | SMAD3GNG2GNB1CYP3A4THRB | |
| SCHEMBL17713858 | 0.76 | SMAD3 (0.46) | SMAD3GNG2GNB1CYP3A4THRB | |
| SCHEMBL6026564 | 0.75 | SMAD3 (0.41) | SMAD3GNG2GNB1CYP3A4THRB | |
| SCHEMBL4478640 | 0.74 | SMAD3 (0.42) | SMAD3GNG2GNB1STK17BCYP3A4 | |
| SCHEMBL20526344 | 0.72 | SMAD3 (0.41) | SMAD3GNG2GNB1CYP3A4THRB | |
| SCHEMBL2167804 | 0.70 | SMAD3 (0.43) | SMAD3GNG2GNB1CYP3A4THRB | |
| SCHEMBL15019692 | 0.70 | GNG2 (0.50) | SMAD3GNG2GNB1THRBRECQL | |
| SCHEMBL29401708 | 0.70 | GNG2 (0.50) | SMAD3GNG2GNB1THRBRECQL | |
| SCHEMBL3717351 | 0.69 | SMAD3 (0.45) | SMAD3GNG2GNB1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070243176-A1 | Human genes and gene expression products | NUVELO, INC. | 2007-10-18 | — | — | US | disclosed |