Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMAD3 | P84022 | 1/20 | 0.43 |
| ▸ | GNG2 | P59768 | 1/20 | 0.42 |
| ▸ | GNB1 | P62873 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401708 | 0.88 | GNG2 (0.50) | SMAD3GNG2GNB1GAAPKM | |
| SCHEMBL15019692 | 0.88 | GNG2 (0.50) | SMAD3GNG2GNB1GAAPKM | |
| SCHEMBL20526344 | 0.85 | SMAD3 (0.41) | SMAD3GNG2GNB1GAAPKM | |
| SCHEMBL20526266 | 0.84 | SMAD3 (0.49) | SMAD3GNG2GNB1GAAPKM | |
| SCHEMBL6823049 | 0.78 | RECQL (0.43) | SMAD3GNG2GNB1GAAPKM | |
| SCHEMBL202849 | 0.77 | RECQL (0.42) | SMAD3GNG2GNB1GAAPKM | |
| SCHEMBL3390818 | 0.77 | TDP1 (0.41) | SMAD3GNG2GNB1GAAPKM | |
| SCHEMBL3717351 | 0.77 | SMAD3 (0.45) | SMAD3GNG2GNB1GAAPKM | |
| SCHEMBL20841470 | 0.76 | GAA (0.42) | SMAD3GNG2GNB1GAAPKM | |
| SCHEMBL31001054 | 0.75 | GNG2 (0.50) | SMAD3GNG2GNB1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371927-B1 | Fluorescent dye compounds, conjugates and uses thereof | LIFE TECHNOLOGIES CORP (US) | 2020-03-11 | — | — | EP | claimed |
| US-8729267-B2 | Fluorescent dye compounds, conjugates and uses thereof | APPLIED BIOSYSTEMS, LLC (US) | 2014-05-20 | — | — | US | claimed |
| US-20110250699-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | Life Technologies Corporation (US) | 2011-10-13 | — | — | US | claimed |
| EP-2371927-A1 | Fluorescent dye compounds, conjugates and uses thereof | Life Technologies Corporation (US) | 2011-10-05 | — | — | EP | claimed |
| US-7985602-B2 | Fluorescent dye compounds, conjugates and uses thereof | APPLIED BIOSYSTEMS, LLC (US) | 2011-07-26 | — | — | US | claimed |
| US-20090093062-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | APPLERA CORPORATION (US) | 2009-04-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093062-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | GFPT1, SLC46A1, SLC7A5 | SMAD3 3741/4885GNG2 1559/4885GNB1 1485/4885 |
| US-20110250699-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | GFPT1, SLC46A1, SLC7A5 | SMAD3 3741/4885GNG2 1559/4885GNB1 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.