Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMAD3 | P84022 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GNG2 | P59768 | 1/20 | 0.35 |
| ▸ | GNB1 | P62873 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701249 | 0.89 | SMAD3 (0.44) | SMAD3MEN1KMT2ATTRTDP1 | |
| SCHEMBL15019692 | 0.76 | GNG2 (0.50) | SMAD3POLBMEN1GAAKMT2A | |
| SCHEMBL29401708 | 0.76 | GNG2 (0.50) | SMAD3POLBMEN1GAAKMT2A | |
| SCHEMBL1230563 | 0.75 | SMAD3 (0.44) | SMAD3MEN1KMT2ALMNATDP1 | |
| SCHEMBL5580100 | 0.74 | SMAD3 (0.39) | SMAD3MEN1GAAKMT2ALMNA | |
| SCHEMBL6026564 | 0.72 | SMAD3 (0.41) | SMAD3MEN1KMT2ATDP1HTT | |
| SCHEMBL8207884 | 0.70 | SMAD3 (0.48) | SMAD3POLBMEN1GAAKMT2A | |
| SCHEMBL1464072 | 0.68 | SMAD3 (0.82) | SMAD3MEN1KMT2ATDP1ALOX15 | |
| SCHEMBL17001191 | 0.67 | SMAD3 (0.45) | SMAD3POLBMEN1GAAKMT2A | |
| SCHEMBL20526344 | 0.67 | SMAD3 (0.41) | SMAD3POLBMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999634-B2 | Nucleic acid detection combining amplification with fragmentation | QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (US) | 2015-04-07 | — | — | US | disclosed |
| US-20090181378-A1 | NUCLEIC ACID DETECTION COMBINING AMPLIFICATION WITH FRAGMENTATION | QUEST DIAGNOSTICS INVESTMENTS LLC | 2009-07-16 | — | — | US | disclosed |