SCHEMBL558025

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11106612	0.81	HAO1 (0.43)	LTA4HTSHRHAO1HTTALDH1A1
	SCHEMBL7760415	0.74	MEN1 (0.45)	HTTALDH1A1MAPK1KMT2AMEN1
	SCHEMBL6771165	0.72	LTA4H (0.41)	LTA4HTSHRHTTCYP1A2CYP2C19
	SCHEMBL1451793	0.69	LTA4H (0.44)	LTA4HTSHRBCAT2HAO1HTT
	SCHEMBL3379912	0.69	CYP1A2 (0.51)	LTA4HTSHRBCAT2HAO1HTT
	SCHEMBL11595065	0.67	LTA4H (0.41)	LTA4HTSHRHTTALDH1A1CYP1A2
	SCHEMBL2521152	0.66	LTA4H (0.58)	LTA4HTSHRBCAT2HAO1HTT
	SCHEMBL4276104	0.66	BCAT2 (0.75)	LTA4HTSHRBCAT2HAO1HTT
	SCHEMBL20240785	0.66	LTA4H (0.57)	LTA4HTSHRHAO1HTTALDH1A1
	SCHEMBL9481848	0.66	LTA4H (0.50)	LTA4HTSHRBCAT2HAO1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.