Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29820228 | 0.84 | CTSB (0.56) | CTSBCTSSCTSKBRD4CREBBP | |
| SCHEMBL507151 | 0.84 | CTSB (0.56) | CTSBCTSSCTSKBRD4CREBBP | |
| SCHEMBL30504293 | 0.83 | HDAC1 (0.56) | CTSBCTSSCTSKBRD4CREBBP | |
| SCHEMBL5581100 | 0.82 | BRD4 (0.49) | CTSBCTSSCTSKBRD4CREBBP | |
| SCHEMBL3728033 | 0.81 | DYRK1A (0.47) | CTSBCTSSCTSKBRD4CREBBP | |
| SCHEMBL18664426 | 0.81 | HDAC1 (0.60) | CTSBCTSSCTSKBRD4CREBBP | |
| SCHEMBL16410240 | 0.80 | BRD4 (0.53) | CTSBCTSSCTSKBRD4CREBBP | |
| SCHEMBL5581535 | 0.79 | BRD4 (0.42) | CTSBCTSSCTSKBRD4CREBBP | |
| SCHEMBL6285318 | 0.79 | CTSL (0.56) | BRD4GAAGLSCTSLKDM4A | |
| SCHEMBL28360519 | 0.79 | BRD4 (0.46) | CTSBCTSSCTSKBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |