Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5580714 | 0.91 | ACACB (0.47) | BRD4CREBBPRAB9AHDAC1APEX1 | |
| SCHEMBL5580792 | 0.82 | CTSB (0.46) | BRD4CREBBPHDAC1CTSBCTSS | |
| SCHEMBL18664426 | 0.81 | HDAC1 (0.60) | BRD4CREBBPHDAC1CTSBCTSS | |
| SCHEMBL5474885 | 0.80 | CTSS (0.50) | BRD4CREBBPRAB9ACTSBCTSS | |
| SCHEMBL30504293 | 0.79 | HDAC1 (0.56) | BRD4CREBBPHDAC1CTSBCTSS | |
| SCHEMBL12305686 | 0.78 | BRD4 (0.57) | BRD4CREBBPHDAC1CTSBCTSS | |
| SCHEMBL24300007 | 0.77 | BRD4 (0.56) | BRD4CREBBPHDAC1CTSBCTSS | |
| SCHEMBL5581535 | 0.77 | BRD4 (0.42) | BRD4CREBBPHDAC1CTSBCTSS | |
| SCHEMBL5580865 | 0.77 | CFD (0.45) | PPARG | |
| SCHEMBL16397304 | 0.77 | FNTA (0.55) | BRD4CREBBPHDAC1CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |