Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.48 |
| ▸ | CTSL | P07711 | 6/20 | 0.48 |
| ▸ | CTSB | P07858 | 5/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 5/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5582056 | 0.84 | CTSB (0.39) | CTSSCTSLCTSBCTSVCTSK | |
| SCHEMBL5581290 | 0.83 | CTSL (0.43) | CTSSCTSLCTSBCTSVKMO | |
| SCHEMBL5519856 | 0.78 | CTSL (0.59) | CTSSCTSLCTSBCTSVCTSK | |
| SCHEMBL5519863 | 0.78 | CTSL (0.59) | CTSSCTSLCTSBCTSVCTSK | |
| SCHEMBL5520635 | 0.67 | CTSL (0.62) | CTSSCTSLCTSBCTSK | |
| SCHEMBL14507768 | 0.67 | MKNK1 (0.72) | KMOSMPD1KDM4E | |
| SCHEMBL1399704 | 0.67 | KMO (0.67) | KMOSUCNR1SMPD1KDM4E | |
| SCHEMBL13626336 | 0.66 | KMO (0.61) | CTSSCTSLCTSBCTSVKMO | |
| SCHEMBL6048160 | 0.65 | CTSL (0.54) | CTSSCTSLCTSBCTSK | |
| SCHEMBL13188259 | 0.65 | KMO (0.69) | KMOSMPD1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007519744-A | — | — | 2007-07-19 | — | — | JP | claimed |
| EP-1716158-A2 | SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | Schering Aktiengesellschaft (DE) | 2006-11-02 | — | — | EP | claimed |
| WO-2005074904-A2 | SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | claimed |
| EP-1716158-A2 | SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | Schering Aktiengesellschaft (DE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005074904-A2 | SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | disclosed |