Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5582092 | 0.90 | LMNA (0.51) | LMNACHRM2ADORA3KCNH2KDM4E | |
| SCHEMBL5581522 | 0.88 | LMNA (0.50) | LMNACHRM2ADORA3KCNH2KDM4E | |
| SCHEMBL28164935 | 0.83 | LMNA (0.45) | LMNACHRM2ADORA3KCNH2KDM4E | |
| SCHEMBL22719989 | 0.82 | LMNA (0.42) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL28310002 | 0.80 | LMNA (0.49) | LMNACHRM2ADORA3KCNH2KDM4E | |
| SCHEMBL17790274 | 0.78 | KDM4E (0.38) | LMNAKCNA3KDM4EALDH1A1CYP1A2 | |
| SCHEMBL26574410 | 0.76 | MEN1 (0.49) | LMNAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL23458410 | 0.75 | MEN1 (0.38) | LMNAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19735554 | 0.74 | MEN1 (0.37) | LMNAKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL12978468 | 0.74 | MEN1 (0.50) | LMNAKDM4EALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840120-B1 | N-Heterocyclic compounds and their use in electronic, optoelectronic and electroluminiscent components | NOVALED AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| EP-1840120-A1 | N-Heterocyclic compounds and their use in electronic, optoelectronic and electroluminiscent components | Novaled AG (DE) | 2007-10-03 | — | — | EP | disclosed |