SCHEMBL22719989

SCHEMBL22719989

OB(O)c1ccc(-c2cccc3c2C(c2ccccc2)(c2ccccc2)c2ccccc2N3)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
MGLL Q99685 2/20 0.41
CHRM2 P08172 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
KCNH2 Q12809 1/20 0.35
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
ENPP2 Q13822 1/20 0.34
CA14 Q9ULX7 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TRPV1 Q8NER1 1/20 0.31
FLT3 P36888 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5582092 0.89 LMNA (0.51) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL5581522 0.87 LMNA (0.50) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL5582199 0.82 LMNA (0.43) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL28164935 0.82 LMNA (0.45) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL28485524 0.81 CA2 (0.40) CA1CA2MGLLCA4CA6
SCHEMBL28310002 0.79 LMNA (0.49) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL18419422 0.76 CA1 (0.44) LMNACA1CA2MGLLCA4
SCHEMBL29586867 0.73 MEN1 (0.53) LMNACA1CA2MGLLCA4
SCHEMBL11896064 0.73 MEN1 (0.53) LMNACA1CA2MGLLCA4
SCHEMBL13599939 0.70 MGLL (0.49) LMNACA1CA2MGLLCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020237885-A1 DARK BLUE THERMAL ACTIVATION DELAYED FLUORESCENT MATERIAL AND PREPARATION METHOD THEREFOR, AND ELECTROLUMINESCENT DEVICE 武汉华星光电半导体显示技术有限公司 2020-12-03 WO claimed
WO-2020237885-A1 DARK BLUE THERMAL ACTIVATION DELAYED FLUORESCENT MATERIAL AND PREPARATION METHOD THEREFOR, AND ELECTROLUMINESCENT DEVICE 武汉华星光电半导体显示技术有限公司 2020-12-03 WO disclosed