SCHEMBL28310002

SCHEMBL28310002

[c]1ccc(-c2cccc3c2C(c2ccccc2)(c2ccccc2)c2ccccc2N3)cc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.49
CHRM2 P08172 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
KCNH2 Q12809 1/20 0.38
MAPT P10636 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
XBP1 P17861 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
KDM4E B2RXH2 1/20 0.30
OPRK1 P41145 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5582092 0.89 LMNA (0.51) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL28964136 0.88 LMNA (0.37) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL5581522 0.88 LMNA (0.50) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL28164935 0.82 LMNA (0.45) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL28657263 0.82 ALOX5 (0.39) LMNACHRM2ADORA3KCNH2MGAM
SCHEMBL18204436 0.81 LMNA (0.41) LMNAMAPTSMN1; SMN2MEN1KMT2A
SCHEMBL5582199 0.80 LMNA (0.43) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL22719989 0.79 LMNA (0.42) LMNACHRM2ADORA3KCNH2MAPT
SCHEMBL22534396 0.79 PDK2 (0.42) LMNA
SCHEMBL28852171 0.77 PDK2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850290-A Organic electroluminescent material based on heteroanthrone five-membered ring and application thereof in OLED 华南理工大学 2023-03-28 CN claimed
CN-115745974-A Chiral near ultraviolet organic electroluminescent material, preparation method thereof and application thereof in CP-OLED 华南理工大学 2023-03-07 CN claimed
CN-113582908-A Near-ultraviolet organic electroluminescent material based on benzene cyano, preparation method thereof and application thereof in preparing OLED 华南理工大学 2021-11-02 CN claimed
CN-110079305-A Navy blue thermal activation delayed fluorescence material and its production method, electroluminescent device 武汉华星光电半导体显示技术有限公司 2019-08-02 CN claimed
CN-113582908-B Near-ultraviolet organic electroluminescent material based on phenylcyano, preparation method thereof and application thereof in OLED preparation 华南理工大学 2023-09-26 CN disclosed
CN-115850290-A Organic electroluminescent material based on heteroanthrone five-membered ring and application thereof in OLED 华南理工大学 2023-03-28 CN disclosed
CN-115745974-A Chiral near ultraviolet organic electroluminescent material, preparation method thereof and application thereof in CP-OLED 华南理工大学 2023-03-07 CN disclosed
CN-113582908-A Near-ultraviolet organic electroluminescent material based on benzene cyano, preparation method thereof and application thereof in preparing OLED 华南理工大学 2021-11-02 CN disclosed
CN-110079305-A Navy blue thermal activation delayed fluorescence material and its production method, electroluminescent device 武汉华星光电半导体显示技术有限公司 2019-08-02 CN disclosed