Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.77 |
| ▸ | METAP1 | P53582 | 2/20 | 0.64 |
| ▸ | CYP24A1 | Q07973 | 6/20 | 0.62 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.62 |
| ▸ | CYP27A1 | Q02318 | 3/20 | 0.59 |
| ▸ | ACHE | P22303 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30667087 | 0.89 | CYP19A1 (0.62) | CYP19A1METAP1CYP24A1CYP26A1ACHE | |
| SCHEMBL7784427 | 0.89 | CYP19A1 (0.62) | CYP19A1METAP1CYP24A1CYP26A1ACHE | |
| Bromide SCHEMBL2403927 | 0.89 | ACHE (0.76) | CYP19A1METAP1CYP24A1CYP26A1ACHE | |
| Hydrochloric Acid SCHEMBL2338476 | 0.89 | ACHE (0.74) | CYP19A1METAP1CYP24A1CYP26A1ACHE | |
| SCHEMBL7245357 | 0.88 | CYP24A1 (0.80) | CYP19A1CYP24A1CYP26A1CYP27A1ACHE | |
| SCHEMBL5582493 | 0.87 | CYP19A1 (0.73) | CYP19A1METAP1CYP24A1CYP26A1CYP27A1 | |
| SCHEMBL30462610 | 0.87 | CYP19A1 (0.73) | CYP19A1METAP1CYP24A1CYP26A1CYP27A1 | |
| SCHEMBL6378154 | 0.87 | CYP19A1 (1.00) | CYP19A1METAP1CYP24A1CYP26A1 | |
| SCHEMBL19748689 | 0.83 | CYP19A1 (0.63) | CYP19A1METAP1CYP24A1CYP26A1ACHE | |
| SCHEMBL15700137 | 0.82 | ACHE (0.80) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070087346-A1 | Orthogonal gene switches | CILIBERTO GENNARO | 2007-04-19 | — | — | US | disclosed |
| US-20070087346-A1 | Orthogonal gene switches | CILIBERTO GENNARO | 2007-04-19 | — | — | US | disclosed |
| US-20070087346-A1 | Orthogonal gene switches | CILIBERTO GENNARO | 2007-04-19 | — | — | US | disclosed |
| EP-1680447-A2 | ORTHOGONAL GENE SWITCHES | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005040212-A2 | ORTHOGONAL GENE SWITCHES | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070087346-A1 | Orthogonal gene switches | TCF12, JUN, TCF7 | CYP19A1 1564/4885METAP1 1869/4885CYP24A1 3605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.