Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RHOA | P61586 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5582627 | 0.85 | PTPN2 (0.53) | ALDH1A1POLBMEN1KMT2ARHOA | |
| SCHEMBL5582931 | 0.82 | HSD11B1 (0.47) | ALDH1A1POLBRHOAHSD11B1MCHR1 | |
| SCHEMBL5582888 | 0.82 | NPC1 (0.47) | POLBHSD11B1MCHR1RAB9A | |
| SCHEMBL14454824 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL5582999 | 0.76 | SLC2A1 (0.53) | — | |
| SCHEMBL4226844 | 0.75 | DGAT1 (0.64) | POLBHSD11B1LMNARAB9A | |
| SCHEMBL4226842 | 0.75 | DGAT1 (0.64) | POLBHSD11B1LMNARAB9A | |
| SCHEMBL4226838 | 0.75 | DGAT1 (0.64) | POLBHSD11B1LMNARAB9A | |
| SCHEMBL3723522 | 0.74 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ALMNAKDM2B | |
| SCHEMBL21928862 | 0.74 | MGLL (0.71) | ALDH1A1POLBMEN1KMT2ARHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | KATO KANEYOSHI | 2007-07-26 | — | — | US | disclosed |
| US-7115750-B1 | Melanin concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | MC1R, MCHR1, MCHR2 | ALDH1A1 1784/4885POLB 4114/4885MEN1 380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.