Methyl 4-Methoxybenzoate

Methyl 4-Methoxybenzoate

SCHEMBL5582912

COC(=O)c1ccc(OC)cc1.c1ccc2c(c1)N2

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.72
CA2 P00918 1/20 0.72
MAPT P10636 6/20 0.58
KMT2A Q03164 3/20 0.58
KDM4E B2RXH2 2/20 0.58
MEN1 O00255 2/20 0.58
TSHR P16473 1/20 0.55
RAB9A P51151 2/20 0.54
ALOX5 P09917 1/20 0.54
CES2 O00748 2/20 0.53
CES1 P23141 2/20 0.53
NPC1 O15118 2/20 0.53
LMNA P02545 2/20 0.53
F10 P00742 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
PKM P14618 1/20 0.49
GAA P10253 1/20 0.49
MAPK1 P28482 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl 4-Methoxybenzoate SCHEMBL28249391 0.85 CA1 (0.84) CA1CA2MAPTKMT2AKDM4E
Methyl 4-Methoxybenzoate SCHEMBL231243 0.85 CA1 (1.00) CA1CA2MAPTKMT2AKDM4E
P-Anisic Acid SCHEMBL5584037 0.84 CA1 (0.71) CA1CA2MAPTKMT2AKDM4E
SCHEMBL5582971 0.83 PLK1 (0.74) CA1CA2KMT2AKDM4ETSHR
Methyl 4-Methoxybenzoate SCHEMBL27405603 0.83 CA1 (0.95) CA1CA2MAPTKMT2AKDM4E
SCHEMBL5582839 0.83 PARP10 (0.72) CA1CA2KMT2ARAB9ACES2
Methyl 4-Methoxybenzoate SCHEMBL28248974 0.81 CA1 (0.91) CA1CA2MAPTKMT2AKDM4E
SCHEMBL2273711 0.80 CA1 (0.88) CA1CA2MAPTKMT2AKDM4E
SCHEMBL269558 0.80 CA1 (0.88) CA1CA2MAPTKMT2AKDM4E
SCHEMBL2188276 0.80 CA1 (0.88) CA1CA2MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070054894-A1 Quinazoline potassium channel inhibitors MERCK & CO., INC. (US) 2007-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070054894-A1 Quinazoline potassium channel inhibitors KCNJ2, KCNH2, KCNH3 CA1 3497/4885CA2 619/4885MAPT 2951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.