Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CES2 | O00748 | 2/20 | 0.59 |
| ▸ | CES1 | P23141 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Anisic Acid SCHEMBL27338972 | 0.87 | CA1 (0.95) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL43335 | 0.84 | CA1 (1.00) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL1157044 | 0.84 | CA1 (1.00) | CA1CA2CES2CES1NPC1 | |
| Methyl 4-Methoxybenzoate SCHEMBL5582912 | 0.84 | CA1 (0.72) | CA1CA2CES2CES1NPC1 | |
| SCHEMBL5582839 | 0.84 | PARP10 (0.72) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL17891327 | 0.82 | CA1 (0.95) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL2130101 | 0.82 | CA1 (0.95) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL414716 | 0.82 | CA1 (0.95) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL15548197 | 0.82 | CA1 (0.95) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL38654440 | 0.82 | CA1 (0.95) | CA1CA2CES2CES1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070054894-A1 | Quinazoline potassium channel inhibitors | MERCK & CO., INC. (US) | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054894-A1 | Quinazoline potassium channel inhibitors | KCNJ2, KCNH2, KCNH3 | CA1 3497/4885CA2 619/4885CES2 2180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.