Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2188552 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KDM4ERAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL5583391 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2187742 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4ECYP2C19CYP2D6NPC1 | |
| SCHEMBL30888845 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2187830 | 0.80 | PTGS2 (0.46) | ALDH1A1KDM4ESMN1; SMN2TDP1MAPT | |
| SCHEMBL5583404 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4ECYP2C19CYP1A2CYP2D6 | |
| SCHEMBL210215 | 0.79 | HTT (0.47) | ALDH1A1KDM4ENPC1L3MBTL1MAPT | |
| SCHEMBL1897076 | 0.77 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2L3MBTL1TDP1MAPT | |
| SCHEMBL12451651 | 0.77 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2L3MBTL1TDP1MAPT | |
| SCHEMBL8756705 | 0.76 | AOC3 (0.49) | CYP2C19CYP1A2CYP2D6L3MBTL1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301049-B2 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2007-11-27 | — | — | US | disclosed |
| US-20040242653-A1 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1399412-A1 | PHOTOLABILE ESTERS AND THEIR USES | The Institute of Cancer Research (GB) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003000644-A1 | PHOTOLABILE ESTERS AND THEIR USES | THE INSTITUTE OF CANCER RESEARCH (GB) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242653-A1 | Photolabile esters and their uses | DIMT1, DCTD, DTYMK | ALDH1A1 2920/4885KDM4E 853/4885CYP2C19 4225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.