SCHEMBL210215

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2187742	0.86	ALDH1A1 (0.53)	HTTMAPTCYP3A4KDM4EALDH1A1
	SCHEMBL4824314	0.84	MAPK1 (0.45)	MAPTALDH1A1TUBB4ATUBBTUBA3C
	SCHEMBL2188552	0.83	ALDH1A1 (0.49)	HTTMAPTCYP3A4KDM4EALDH1A1
	SCHEMBL2187830	0.82	PTGS2 (0.46)	HTTMAPTCYP3A4KDM4EALDH1A1
	SCHEMBL4820348	0.80	TUBB4A (0.47)	HTTMAPTALDH1A1TUBB4ATUBB
	SCHEMBL1309457	0.80	ABCB1 (0.47)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL4820656	0.79	TUBB4A (0.56)	CYP3A4ALDH1A1TUBB4ATUBBTUBA3C
	SCHEMBL5583291	0.79	ALDH1A1 (0.44)	MAPTCYP3A4KDM4EALDH1A1ALOX15
	SCHEMBL6551658	0.79	CYP3A4 (0.51)	HTTMAPTCYP3A4KDM4EALDH1A1
	SCHEMBL19548280	0.78	HTT (0.53)	HTTMAPTCYP3A4KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.