Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12451651 | 0.89 | ALDH1A1 (0.44) | ALDH1A1TDP1LMNAMAPTMEN1 | |
| SCHEMBL1897076 | 0.89 | ALDH1A1 (0.44) | ALDH1A1TDP1LMNAMAPTMEN1 | |
| SCHEMBL2187830 | 0.87 | PTGS2 (0.46) | ALDH1A1TDP1LMNAMAPTMEN1 | |
| SCHEMBL5583291 | 0.87 | ALDH1A1 (0.44) | ALDH1A1TDP1LMNAMAPTMEN1 | |
| SCHEMBL2187742 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TDP1LMNAMAPTMEN1 | |
| SCHEMBL210215 | 0.83 | HTT (0.47) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8726011 | 0.79 | CNR2 (0.50) | ALDH1A1TDP1MAPTCYP3A4L3MBTL1 | |
| SCHEMBL10478141 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TDP1LMNAMAPTMEN1 | |
| SCHEMBL11618422 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TDP1LMNAMAPTMEN1 | |
| SCHEMBL6551658 | 0.79 | CYP3A4 (0.51) | ALDH1A1TDP1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102171181-A | N- (alpha-aryl-substituted-2-nitro-4, 5-dialkoxybenzyloxycarbonyl) amine compound and process for producing the same | SHOWA DENKO KK | 2011-08-31 | — | — | CN | disclosed |
| US-20110172421-A1 | N-(alpha-AROMATIC GROUP-SUBSTITUTED-2-NITRO-4,5-DIALKOXYBENZYLOXYCARBONYL)AMINE COMPOUND AND PROCESS FOR PRODUCING THE SAME | SHOWA DENKO K.K. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-7301049-B2 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2007-11-27 | — | — | US | disclosed |
| US-20040242653-A1 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1399412-A1 | PHOTOLABILE ESTERS AND THEIR USES | The Institute of Cancer Research (GB) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003000644-A1 | PHOTOLABILE ESTERS AND THEIR USES | THE INSTITUTE OF CANCER RESEARCH (GB) | 2003-01-03 | — | — | WO | disclosed |
| US-3932392-A | DICYCLOHEXYLAMINE, DIISOPROPYLAMINE | BRISTOL-MYERS COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172421-A1 | N-(alpha-AROMATIC GROUP-SUBSTITUTED-2-NITRO-4,5-DIALKOXYBENZYLOXYCARBONYL)AMINE COMPOUND AND PROCESS FOR PRODUCING THE SAME | NME2, DAO, NMBR | ALDH1A1 982/4885TDP1 963/4885LMNA 1967/4885 |
| US-20040242653-A1 | Photolabile esters and their uses | DIMT1, DCTD, DTYMK | ALDH1A1 2920/4885TDP1 177/4885LMNA 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.