Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | AQP1 | P29972 | 2/20 | 0.32 |
| ▸ | TDP2 | O95551 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596968 | 0.88 | KDM1A (0.36) | — | |
| SCHEMBL4597245 | 0.85 | FFAR4 (0.31) | — | |
| SCHEMBL4597571 | 0.85 | PGR (0.35) | TDP2 | |
| SCHEMBL5583554 | 0.82 | PARP1 (0.40) | AHRAQP1 | |
| SCHEMBL4597165 | 0.82 | NPC1 (0.37) | — | |
| SCHEMBL4596319 | 0.79 | CYP1A2 (0.41) | — | |
| SCHEMBL4706707 | 0.79 | DHODH (0.36) | AQP1 | |
| SCHEMBL4230632 | 0.79 | AQP1 (0.54) | AHRAQP1HTR2CHTR2B | |
| SCHEMBL4595105 | 0.78 | TAAR1 (0.36) | HTR2C | |
| SCHEMBL4963747 | 0.78 | AQP1 (0.47) | AHRAQP1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007509174-A | — | — | 2007-04-12 | — | — | JP | claimed |
| EP-1675840-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2006-07-05 | — | — | EP | claimed |
| WO-2005044812-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH A CORPORATION OF THE STATE OF DELAWARE (US) | 2005-05-19 | — | — | WO | claimed |