Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.53 |
| ▸ | BRAF | P15056 | 4/20 | 0.53 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | TEK | Q02763 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583862 | 0.89 | KDR (0.55) | KDRBRAFMAPTGAAMAPK1 | |
| SCHEMBL5583760 | 0.86 | STK39 (0.56) | KDRSTK39GAAAURKAKIT | |
| SCHEMBL14284626 | 0.85 | GAA (0.68) | KDRBRAFMAPTGAAMAPK1 | |
| SCHEMBL5583823 | 0.83 | PGR (0.55) | KDRSTK39MAPTKITPGR | |
| SCHEMBL14284578 | 0.83 | KDR (0.51) | KDRBRAFMAPTMAPK14AURKA | |
| SCHEMBL5583779 | 0.83 | KDR (0.52) | KDRSTK39KITPGRAR | |
| SCHEMBL14284574 | 0.83 | GRM4 (0.49) | KDRMAPTGAAPGRAR | |
| SCHEMBL14284605 | 0.83 | P2RY1 (0.49) | KDRBRAFMAPTGAAMAPK1 | |
| SCHEMBL14284606 | 0.82 | MAPT (0.57) | KDRBRAFMAPTGAAMAPK1 | |
| SCHEMBL14284609 | 0.82 | KDR (0.58) | KDRBRAFMAPTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |