SCHEMBL5583760

SCHEMBL5583760

COc1ccnc(C(=O)Nc2ccc(Oc3ccccc3)c(C)c2)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STK39 Q9UEW8 1/20 0.56
PGR P06401 1/20 0.54
AR P10275 1/20 0.54
AURKB Q96GD4 3/20 0.49
AURKA O14965 2/20 0.49
TPX2 Q9ULW0 2/20 0.49
DHODH Q02127 1/20 0.48
GRM4 Q14833 2/20 0.47
PDGFRA P16234 4/20 0.47
KIT P10721 2/20 0.47
AXL P30530 1/20 0.47
KDR P35968 2/20 0.47
RAB9A P51151 2/20 0.46
KDM4E B2RXH2 1/20 0.46
NPC1 O15118 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
PARG Q86W56 1/20 0.46
GAA P10253 1/20 0.45
HTT P42858 1/20 0.45
MEN1 O00255 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583823 0.93 PGR (0.55) STK39PGRARPDGFRAKIT
SCHEMBL5583779 0.92 KDR (0.52) STK39PGRARPDGFRAKIT
SCHEMBL5583775 0.88 PNLIP (0.58) STK39GRM4AXLSMN1; SMN2PARG
SCHEMBL14284574 0.87 GRM4 (0.49) PGRARGRM4PDGFRAKDR
SCHEMBL14284575 0.87 GAA (0.58) GRM4PDGFRAKITAXLKDR
SCHEMBL2237038 0.87 RAB9A (0.53) PGRARPDGFRAKITAXL
SCHEMBL5583565 0.86 KDR (0.53) STK39PGRARAURKBAURKA
SCHEMBL5583625 0.86 STK39 (0.57) STK39PDGFRAKITAXLKDR
SCHEMBL5583770 0.86 GRM4 (0.52) PGRGRM4PDGFRAKDRRAB9A
SCHEMBL14284584 0.84 GRM4 (0.52) GRM4PDGFRAKDRRAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed