SCHEMBL5583779

SCHEMBL5583779

COc1ccnc(C(=O)Nc2ccc(Oc3ccc(C)cc3)c(C)c2)c1O

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDR P35968 5/20 0.52
PDGFRA P16234 5/20 0.52
PGR P06401 1/20 0.52
AR P10275 1/20 0.52
MAPK9 P45984 1/20 0.51
PARG Q86W56 2/20 0.47
STK39 Q9UEW8 1/20 0.46
AXL P30530 2/20 0.45
MET P08581 2/20 0.44
TDO2 P48775 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PNLIP P16233 1/20 0.43
KIT P10721 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583823 0.95 PGR (0.55) KDRPDGFRAPGRARMAPK9
SCHEMBL5583760 0.92 STK39 (0.56) KDRPDGFRAPGRARPARG
SCHEMBL5584061 0.90 PARG (0.60) KDRPDGFRAMAPK9PARGSTK39
SCHEMBL5583670 0.89 KDR (0.55) KDRPDGFRAMAPK9AXLMET
SCHEMBL5583717 0.87 KDR (0.48) KDRPDGFRAMAPK9PARGSTK39
SCHEMBL14284570 0.85 PDGFRA (0.48) KDRPDGFRAMAPK9NPC1RAB9A
SCHEMBL5583684 0.85 KDM4E (0.55) KDRPDGFRAMAPK9TDO2NPC1
SCHEMBL14284575 0.85 GAA (0.58) KDRPDGFRAMAPK9AXLMET
SCHEMBL5583729 0.83 PNLIP (0.57) KDRPDGFRAPARGSTK39PNLIP
SCHEMBL5583565 0.83 KDR (0.53) KDRPGRARSTK39MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed