SCHEMBL5583614

SCHEMBL5583614

CCOc1ccc(ONc2cccc(Cl)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.60
FADS1 O60427 1/20 0.52
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
TP53 P04637 2/20 0.46
MAPT P10636 5/20 0.44
ALDH1A1 P00352 3/20 0.44
GAA P10253 2/20 0.44
TAS1R3 Q7RTX0 1/20 0.44
TAS1R1 Q7RTX1 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NQO1 P15559 1/20 0.44
FBP1 P09467 1/20 0.43
EGFR P00533 1/20 0.42
KDM4E B2RXH2 3/20 0.42
NPC1 O15118 1/20 0.42
HPGD P15428 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9818933 0.83 LMNA (0.44) ALOX15FADS1KMT2AMEN1MAPT
SCHEMBL5583697 0.80 LTA4H (0.57) KMT2AMEN1TP53MAPTALDH1A1
SCHEMBL633344 0.80 HTT (0.54) FADS1KMT2AMEN1TP53MAPT
SCHEMBL4112399 0.77 MEN1 (0.76) FADS1KMT2AMEN1TP53MAPT
Hydrochloric Acid SCHEMBL8021451 0.75 MAOB (0.49) KMT2AMEN1TP53MAPTALDH1A1
SCHEMBL5174837 0.75 MEN1 (0.73) FADS1KMT2AMEN1TP53MAPT
SCHEMBL315808 0.74 TP53 (0.59) ALOX15FADS1KMT2AMEN1TP53
SCHEMBL30167806 0.74 TP53 (0.59) ALOX15FADS1KMT2AMEN1TP53
SCHEMBL29997393 0.73 TAAR1 (0.53) ALOX15KMT2ATP53MAPTALDH1A1
SCHEMBL28844861 0.72 ALOX15 (0.43) ALOX15FADS1KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed