SCHEMBL5583624

SCHEMBL5583624

O=C(Nc1ccc(Cc2ccccc2)cc1)c1ncccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN2 Q96KS0 1/20 0.54
FTO Q9C0B1 1/20 0.54
PARP1 P09874 1/20 0.50
GRM4 Q14833 4/20 0.49
CSF1R P07333 1/20 0.49
RET P07949 1/20 0.49
PDGFRB P09619 1/20 0.49
KIT P10721 1/20 0.49
PDGFRA P16234 1/20 0.49
FLT3 P36888 1/20 0.49
LMNA P02545 4/20 0.48
NPC1 O15118 1/20 0.48
TP53 P04637 1/20 0.48
RAB9A P51151 1/20 0.48
KDM4E B2RXH2 2/20 0.48
ATR Q13535 1/20 0.48
PIM1 P11309 1/20 0.46
FLT1 P17948 1/20 0.46
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13201028 0.87 ATR (0.61) EGLN2FTOGRM4CSF1RRET
SCHEMBL5583780 0.81 PNLIP (0.63) LMNANPC1TP53RAB9AHPGD
SCHEMBL18027788 0.80 KDM4E (0.73) EGLN2FTOGRM4CSF1RRET
SCHEMBL14284354 0.80 TLR7 (0.67) EGLN2FTOGRM4CSF1RRET
SCHEMBL18993449 0.80 CSF1R (0.53) EGLN2FTOGRM4CSF1RRET
SCHEMBL5583817 0.77 MAPT (0.56) LMNANPC1TP53RAB9AKDM4E
SCHEMBL21186010 0.77 MAPT (0.52) LMNANPC1TP53RAB9AKDM4E
SCHEMBL31026221 0.77 EGLN2 (0.68) EGLN2FTOALDH1A1MAPK1HTT
SCHEMBL18010076 0.76 CSF1R (0.50) EGLN2FTOGRM4CSF1RRET
SCHEMBL30848531 0.74 NAMPT (0.59) EGLN2FTOGRM4CSF1RRET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed