Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.53 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | KIT | P10721 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 7/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13201028 | 0.85 | ATR (0.61) | CSF1RRETPDGFRBKITPDGFRA | |
| SCHEMBL14284354 | 0.84 | TLR7 (0.67) | CSF1RRETPDGFRBKITPDGFRA | |
| SCHEMBL18027788 | 0.84 | KDM4E (0.73) | CSF1RRETPDGFRBKITPDGFRA | |
| SCHEMBL18010076 | 0.81 | CSF1R (0.50) | CSF1RRETPDGFRBKITPDGFRA | |
| SCHEMBL5583624 | 0.80 | EGLN2 (0.54) | CSF1RRETPDGFRBKITPDGFRA | |
| SCHEMBL5583780 | 0.80 | PNLIP (0.63) | — | |
| SCHEMBL18993387 | 0.78 | P2RX7 (0.47) | KDM4EGRM4PRKCIALDH1A1GAA | |
| SCHEMBL18993400 | 0.78 | KDM4E (0.52) | KDM4EGRM4PRKCIALDH1A1GAA | |
| SCHEMBL14284356 | 0.77 | KDM4E (0.61) | CSF1RRETPDGFRBKITPDGFRA | |
| SCHEMBL5884035 | 0.76 | DEGS1 (0.56) | CSF1RRETPDGFRBKITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682931-B2 | Aryloyl(oxy or amino)pentafluorosulfanylbenzene compound, pharmaceutically acceptable salt thereof, and prodrugs thereof | UBE INDUSTRIES, LTD. (JP) | 2017-06-20 | — | — | US | disclosed |