SCHEMBL5583780

SCHEMBL5583780

O=C(Nc1ccc(Oc2ccccc2)cc1)c1ncccc1O

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PNLIP P16233 4/20 0.63
NPC1 O15118 3/20 0.60
RAB9A P51151 3/20 0.60
ATM Q13315 1/20 0.60
PGR P06401 1/20 0.57
KDR P35968 2/20 0.55
KMT2A Q03164 1/20 0.53
MAPT P10636 1/20 0.52
MAPK1 P28482 1/20 0.52
TP53 P04637 2/20 0.51
RECQL P46063 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
HPGD P15428 1/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13201028 0.87 ATR (0.61) KMT2AMAPTTP53HPGDLMNA
SCHEMBL5583813 0.86 CSF1R (0.55) NPC1RAB9AATMMAPK1SMN1; SMN2
SCHEMBL14284358 0.86 TLR7 (0.62) NPC1RAB9AKDRMAPT
SCHEMBL5583621 0.84 TLR7 (0.57) KDR
SCHEMBL14284685 0.81 PNLIP (0.68) PNLIPNPC1RAB9APGRKDR
SCHEMBL5583624 0.81 EGLN2 (0.54) NPC1RAB9AKMT2AMAPTMAPK1
SCHEMBL2238143 0.80 PNLIP (0.56) PNLIPNPC1RAB9APGRKDR
SCHEMBL7642204 0.80 ALDH1A1 (0.58) NPC1RAB9APGRKDRKMT2A
SCHEMBL18993449 0.80 CSF1R (0.53)
SCHEMBL18027788 0.80 KDM4E (0.73) PNLIPNPC1RAB9AKDRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed